0-2629-0191-5
Bangkhunprom , Phranakorn Bangkok, Thailand
@LINEOA
Microwave Peptide Synthesizer

Liberty Blue 2.0

AWIONS CUBE

The Liberty Blue™ 2.0 is an ultra-efficient microwave peptide synthesizer, delivering high-quality peptides with record low waste generation and synthesis times. Through partnering CEM’s patented and published No-Wash methodology with flexible and intuitive system controls, the Liberty Blue 2.0 opens up a world of more efficient, high-yielding, and structurally complex syntheses than ever thought possible.

  • <4 minutes per amino acid (AA) addition (includes coupling through deprotection, scales under 0.5 mmol)
  • <6 mL waste generated per AA addition (includes coupling through deprotection, scales under 0.2 mmol )
  • 0.005 to 5 mmol synthesis scale range
  • HT accessories available for queueing up to 12 syntheses
  • 21CFR Part 11 compliant software

*ดาวน์โหลดโบรชัวร์ Liberty Blue 2.0

Ultra Efficient – Solid Phase Peptide Synthesis (UE-SPPS)

New “No Wash” approach, same clean peptides.

With this Liberty system comes the revolutionary UE-SPPS methodology; total wash elimination. Through a remarkable combination of methodology optimization, reagent selection, and engineering advancements, CEM’s “No Wash” technology reduces waste production by up to 95%, and all without sacrificing synthesis yield and purity.

Unmatched Peptide Quality

A new level of peptide purity.

With advancements in system fluidics, reaction vessel environment, and chemistry methodology achieve better synthesis results than ever before

Better Chemistry

  • Carbodiimide coupling strategy for reduced epimerization and side reactions
  • ProTide resin development for optimized loading and swelling parameters
  • Microwave heating approach for improved reaction efficiency and synthesis results

Better Engineering

  • Headspace flushing technology for cleaner reaction environment
  • Optimized flow paths for simple and efficient reagent delivery
  • Digitally variable N₂ control for enhanced bubbling, purging, and draining

Semaglutide (Crude)
Length: 31 Amino Acids

Scale: 0.1 mmol
Synthesis Time: ~ 1 hour, 50 minutes

Waste: 135 mL (Liberty PRIME 2.0) or 238 mL (Liberty Blue 2.0)

1-42β-amyloid (Crude)
Length: 42 Amino Acids

Scale: 0.1 mmol
Synthesis Time: ~ 2 hours, 30 minutes

Waste: 179 mL (Liberty PRIME 2.0) or 316 mL (Liberty Blue 2.0)

Proinsulin (Crude)
Length: 86 Amino Acids

Scale: 0.1 mmol

Synthesis Time: ~ 10 hours, 40 minutes

Waste: 687 mL (Liberty PRIME 2.0) or 973 mL (Liberty Blue 2.0)

Software Flexible, Powerful, Traceable

With flexible and easy-to-use software, nothing will stand between you and your synthesis. Powerful calculator and maintenance tools simplify system operation while thorough logging and audit trailing protect traceability.

Enter the Parameters

The method editor on the Liberty Blue allows full customization of reaction parameters.

Pause, Edit, Monitor at any Step

Easily pause, edit, and monitor reactions from the run screen.


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